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Product details
名称
Frexalimab (anti-CD40L)
分子类型
抗体
英文别名
HIGM1 | T-B cell-activating molecule | T-BAM | T-cell antigen Gp39 | TNF-related activation protein | TNFSF5 | TNFSF5IMD3 | TRAP | TRAPtumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) | tumor necrosis factor (ligand) superfamily m
货号
Ab182964-100μg
包装规格
100μg
级别
无动物源
浓度
≥95%(SDS-PAGE&SEC-HPLC)
储存温度
-80℃储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂
No
生化机理
在没有共刺激的情况下介导 B 细胞增殖,在有 IL-4 的情况下介导 IgE 的产生。参与免疫球蛋白类的转换。血小板释放可溶性 CD40L 部分受 GP IIb/IIIa、肌动蛋白聚合和基质金属蛋白酶(MMP)抑制剂敏感途径的调节。 翻译后:可溶性形式通过蛋白水解加工从膜形式衍生而来。连接的糖是高甘露糖和复合型糖的混合物。聚糖结构不影响与 CD40 的结合亲和力。未进行 O 型糖基化。
宿主种属
人(Human)
种属反应性
人(Human)
特异性
CD40LG
CAS编号和信息
2515463-86-0
SDS-PAGE
145.66 kDa
偶联
Unconjugated
亚型
Human IgG1
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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Research chemical 40L; ≥95%; HPLC

Research chemical 40L; ≥95%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 40L; ≥95%; HPLC.

item number:Ab182964-100μg
Product model:100μg
level: 40L; ≥95%; HPLC
Lead Time:30days
sold 635 Items
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Specifications:

100μg

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