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Product details

名称

Caspase-9 Mouse mAb

分子类型

抗体

别名

半胱氨酸天冬氨酸蛋白酶9 | 半胱氨天冬酶9抗体 | Caspase-9/CASP9 抗体 | CASP9 抗体

英文别名

货号

Ab183845-10μl

包装规格

10μl

级别

无载体

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃ (1-2周); 长期储存-20℃ (24个月); 收货后建议分装，避免反复冻融.

储存缓冲液

PBS, pH 7.2

生化机理

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC.

免疫原

Recombinant protein corresponding to Human Caspase-9

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human Caspase-9

阳性对照

WB: HeLa, HepG2, K562 and HEK293 whole cell lysates Flow Cytometry: K562 cells IF/ICC: HeLa cells

SDS-PAGE

150.0 KDa

偶联

Unconjugated

亚型

Mouse IgG2b

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

GH01/4B9

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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