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Product details

名称

N Cadherin Mouse mAb

分子类型

抗体

别名

英文别名

货号

Ab183886-10μl

包装规格

10μl

级别

无载体

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

储存缓冲液

PBS, pH 7.2

生化机理

Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). Required for proper neurite branching. Required for pre- and postsynaptic organization (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density

免疫原

Recombinant protein corresponding to Human N Cadherin

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

N Cadherin

阳性对照

WB: HeLa, HEK293, SH-N-SH and SH-SY5Y whole cell lysates

SDS-PAGE

150.0 KDa

偶联

Unconjugated

亚型

Mouse IgG2b

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

AB02/1F1

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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