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Product details
名称
Integrin beta 7 Rat mAb (APC)
分子类型
抗体
别名
整合素β7抗体 | Integrin beta 7抗体 | 交联别藻蓝蛋白偶联的Anti-Integrin beta 7抗体[FIB504] | 整合素 β7 大鼠 mAb (APC)
英文别名
Ly69 | Gut homing receptor beta subunit | integrin beta 7 subunit | Integrin beta 7 | integrin beta-7 | integrin, beta 7 | ITGB7 | Gut homing receptor beta subunit antibody | Integrin beta 7 subunit antibody | Integrin beta-7 antibody | Integrin beta-P an
货号
Ab190044-10μg
包装规格
10μg
级别
已验证
浓度
0.5 mg/mL
储存温度
2-8°C储存,避光,禁止冷冻
运输条件
冰袋运输
稳定性与储存
未稀释的抗体溶液应保存在 2°C 至 8°C 之间,避免长时间暴露在光线下。切勿冷冻。
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
生化机理
整合素α-4/β-7(佩尔斑块特异性归巢受体 LPAM-1)是一种粘附分子,可介导淋巴细胞迁移并归巢到肠道相关淋巴组织(GALT)。整合素α-4/β-7 与细胞表面粘附分子 MADCAM1 相互作用,MADCAM1 通常由胃肠道血管内皮表达。它还与 VCAM1 和细胞外基质成分纤维连接蛋白相互作用。它能识别纤维粘连蛋白替代剪接 CS-1 区域中的一个或多个结构域。相互作用涉及 MADCAM1 中的三肽 L-D-T 和纤维粘连蛋白中的 L-D-V。与 HIV-1 gp120 结合,从而使病毒进入 GALT,这被认为是艾滋病的主要诱因。相互作用涉及 HIV-1 gp120 中的三肽 L-D-I。整合素α-E/β-7(HML-1)是 E-cadherin 的受体。
免疫原
TK1 cells
宿主种属
大鼠(Rat)
种属反应性
人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)
特异性
Integrin beta 7
阳性对照
Flow: Human peripheral blood lymphocytes.
偶联
APC
亚型
Rat IgG2a
克隆类型
单克隆抗体
轻链亚型
kappa
纯化方法
Protein G purified
克隆号
FIB504
Excitation(nm)
Red Laser(633nm)
Emission(nm)
660nm
Ex/Em(nm)
Ex:650nm;Em:660nm
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical 0. 5 mg

Research chemical 0. 5 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 0. 5 mg.

item number:Ab190044-10μg
Product model:10μg
level: 0. 5 mg
Lead Time:30days
sold 290 Items
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10μg

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