Share to
Details
Safety
Related
Technical Documents
Articles
reviews
Consult
returns
Product details
名称
CD31 Rat mAb (APC)
分子类型
抗体
别名
血小板内皮细胞粘附分子1(PECAM1)抗体 | CD31抗体 | 交联别藻蓝蛋白偶联的大鼠抗小鼠CD31抗体 | CD31 大鼠单克隆抗体 (APC) | CD31 大鼠单抗 (APC)
英文别名
Cd31 | Pecam | adhesion molecule | CD31 antigen | CD31/EndoCAM | EndoCAM | FLJ34100 | FLJ58394 | GPIIA' | PECA1 | PECAM1 | PECAM-1 | PECAM-1, CD31/EndoCAM | platelet endothelial cell adhesion molecule | platelet endothelial cell adhesion molecule-1 | plat
货号
Ab190236-10μg
包装规格
10μg
级别
已验证
浓度
0.5 mg/mL
储存温度
2-8°C储存,避光,禁止冷冻
运输条件
冰袋运输
稳定性与储存
未稀释的抗体溶液应保存在 2°C 至 8°C 之间,避免长时间暴露在光线下。切勿冷冻。
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
生化机理
诱发动脉粥样硬化(相似)。在大多数炎症条件下,白细胞跨内皮迁移(TEM)都需要这种细胞粘附分子。Tyr-690 在 TEM 中起着关键作用,是 PECAM1 有效运入和运出外侧边界再循环区(LBRC)的必要条件,也是 LBRC 膜锁定迁移白细胞周围的必要条件。通过传递 "分离 "信号,防止吞噬细胞吞噬紧贴的存活细胞,并在细胞凋亡时改变功能,促进凋亡细胞与吞噬细胞的系留(存活细胞与吞噬细胞相遇时,通过双方细胞表面的 PECAM1 的亲同性相互作用,导致存活细胞被吞噬细胞主动排斥。在细胞凋亡过程中,PECAM1 由内而外的信号传递在某种程度上失效,因此凋亡细胞不再主动排斥吞噬细胞。由于缺乏这种排斥信号,加上 "吃我 "信号与各自受体的相互作用,导致凋亡细胞附着在吞噬细胞上,从而引发吞噬过程)。同工酶 Delta15 无法防止细胞凋亡。调节 BDKRB2 的激活。调节缓激肽和高渗冲击诱导的人脐带静脉细胞(HUVEC)ERK1/2 的活化。
免疫原
C3H/HeJ mouse hematopoietic progenitor cell line 3
宿主种属
大鼠(Rat)
种属反应性
小鼠(Mouse)
特异性
CD31
阳性对照
Flow: C57BL/6 mouse splenocytes.
SDS-PAGE
150 kDa
偶联
APC
亚型
Rat IgG2a
克隆类型
单克隆抗体
轻链亚型
kappa
纯化方法
Protein G purified
克隆号
390
Excitation(nm)
Red Laser(633nm)
Emission(nm)
660nm
Ex/Em(nm)
Ex:650nm;Em:660nm
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical 0. 5 mg

Research chemical 0. 5 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 0. 5 mg.

item number:Ab190236-10μg
Product model:10μg
level: 0. 5 mg
Lead Time:30days
sold 629 Items
Ask Solution engineer
Specifications:

10μg

Qty

Recommended for you