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名称

CD45R Rat mAb (Biotin)

分子类型

抗体

别名

蛋白酪氨酸磷酸酶受体C(CD45)抗体 | CD45R抗体 | Biotin 标记Anti-CD45R抗体[RA3-6B2]；生物素标记的抗CD45R抗体 | CD45R 大鼠 mAb（生物素）

英文别名

LCA | CD45 | T200 | GP180 | IMD105 | B220 | CD45 antigen | CD45R | EC 3.1.3.48 | L-CA | LY5 | protein tyrosine phosphatase, receptor type, C | receptor-type tyrosine-protein phosphatase C | T200 glycoprotein | T200 leukocyte common antigen | T200receptor

货号

Ab191650-10μg

包装规格

10μg

级别

已验证

浓度

0.5 mg/mL

储存温度

2-8°C储存,避光,禁止冷冻

运输条件

冰袋运输

稳定性与储存

未稀释的抗体溶液应保存在 2°C 至 8°C 之间，避免长时间暴露在光线下。切勿冷冻。

储存缓冲液

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

防腐剂

0.05% Proclin300

生化机理

通过抗原受体激活 T 细胞所需的蛋白酪氨酸蛋白磷酸酶。与 DPP4 结合后，可作为 T 细胞共激活的正向调节因子。第一个 PTPase 结构域具有酶活性，而第二个 PTPase 结构域似乎会影响第一个 PTPase 结构域的底物特异性。T 细胞活化后，该蛋白可招募 SKAP1 和 FYN 并使其去磷酸化。

免疫原

Abelson murine leukemia virus-induced pre-B tumor cells

宿主种属

大鼠(Rat)

种属反应性

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

特异性

CD45R

阳性对照

Flow: C57BL/6 mouse splenocytes.

SDS-PAGE

26.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 207.1 kDa, under non-reducing conditions.

偶联

Biotin

亚型

Rat IgG2a

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

RA3-6B2

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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