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Product details

名称

Ligufalimab (anti-CD47)

分子类型

抗体

别名

莱法利单抗

英文别名

货号

Ab191922-100μg

包装规格

100μg

级别

无动物源

浓度

≥95%(SDS-PAGE&SEC-HPLC)

储存温度

-80℃储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0

防腐剂

生化机理

通过充当血小板上 THBS1 的粘附受体，在细胞粘附和调节整合素方面发挥作用。在海马的记忆形成和突触可塑性中发挥重要作用（相似）。SIRPA 的受体，与之结合可阻止未成熟树突状细胞的成熟，并抑制成熟树突状细胞产生细胞因子。与 SIRPG 相互作用可介导细胞-细胞粘附，增强超抗原依赖性 T 细胞介导的增殖，并刺激 T 细胞活化。可能在膜运输和/或依赖整合素的信号转导中发挥作用。可防止红细胞过早消亡。可能参与病毒感染后引起的膜通透性变化。

宿主种属

人(Human)

种属反应性

人(Human), 食蟹猴(Cynomolgus monkey) | 人(Human),食蟹猴(Cynomolgus monkey)

特异性

CD47

CAS编号和信息

2428381-55-7

SDS-PAGE

144.58 kDa

偶联

Unconjugated

亚型

Human IgG4SP

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！