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Product details
名称
Lendalizumab (anti-Complement C5)
分子类型
抗体
别名
奥仑达利珠单抗 | 棱德里珠单抗
英文别名
Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen
货号
Ab191930-100μg
包装规格
100μg
级别
无动物源
浓度
≥95%(SDS-PAGE&SEC-HPLC)
储存温度
-80℃储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂
No
生化机理
C5 转化酶激活 C5 后,后期补体成分 C5-C9 就会自发组装成膜攻击复合体。C5b 有一个与 C6 瞬时结合的位点。C5b-C6 复合物是裂解复合物组装的基础。由补体 C5 蛋白水解降解而来的 C5 无乳毒素是局部炎症过程的介质。它能诱导平滑肌收缩,增加血管通透性,并导致肥大细胞和嗜碱性白细胞释放组胺。C5a 还能刺激多形核白细胞运动(趋化作用),并引导它们向炎症部位迁移(趋化作用)。
宿主种属
人(Human)
种属反应性
人(Human)
特异性
C5
CAS编号和信息
2210314-30-8
SDS-PAGE
145 kDa
偶联
Unconjugated
亚型
Human IgG2SA
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical ≥95%; HPLC

Research chemical ≥95%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%; HPLC.

item number:Ab191930-100μg
Product model:100μg
level: ≥95%; HPLC
Lead Time:30days
sold 598 Items
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Specifications:

100μg

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