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Product details

名称

Brolucizumab (anti-VEGFA)

分子类型

抗体

别名

布洛赛珠单抗 | VEGFA抗体 | VEGFA单克隆抗体 | VEGFA药靶抗体

英文别名

货号

Ab191965-100μg

包装规格

100μg

级别

无动物源

浓度

≥95%(SDS-PAGE&SEC-HPLC)

储存温度

-80℃储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0

防腐剂

生化机理

血管生成、血管生成和内皮细胞生长过程中的活跃生长因子。诱导内皮细胞增殖、促进细胞迁移、抑制细胞凋亡并诱导血管通透。与 FLT1/VEGFR1 和 KDR/VEGFR2 受体、硫酸肝素和肝素结合。NRP1/Neuropilin-1 与 VEGF-165 和 VEGF-145 异构体结合。异构体 VEGF165B 可与 KDR 结合，但不会激活下游信号通路，不会激活血管生成并抑制肿瘤生长。

宿主种属

人(Human)

种属反应性

人(Human)

特异性

VEGFA

CAS编号和信息

1531589-13-5

SDS-PAGE

52.04 kDa

偶联

Unconjugated

亚型

Human IgG1-CS

克隆类型

重组抗体

纯化方法

Protein A purified

Format

scFv

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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