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Product details

名称

NCI m972 (anti-CD22)

分子类型

抗体

别名

英文别名

货号

Ab209824-100μg

包装规格

100μg

级别

无动物源

浓度

≥95%(SDS-PAGE&SEC-HPLC)

储存温度

-80℃储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.

储存缓冲液

Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0

防腐剂

生化机理

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

宿主种属

人(Human)

种属反应性

人(Human)

特异性

CD22

SDS-PAGE

144.3 kDa

偶联

Unconjugated

亚型

Human IgG1

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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