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名称
CD46 Mouse mAb
分子类型
抗体
别名
膜辅蛋白 | Anti-CD46抗体 | CD46小鼠单克隆抗体 | 小鼠抗人CD46抗体 | CD46抗体 | Anti-MCP抗体 | MCP小鼠单克隆抗体 | 小鼠抗人MCP抗体 | MCP抗体 | Anti-MIC10抗体 | MIC10小鼠单克隆抗体 | 小鼠抗人MIC10抗体 | MIC10抗体
英文别名
AHUS2 antibody | Antigen defined by monoclonal antibody TRA 2 10 antibody | Antigen identified by monoclonal antibody TRA 2 10 antibody | CD46 antibody | CD46 antigen antibody | CD46 antigen complement regulatory protein antibody | CD46 molecule antibody
货号
Ab210969-10μl
包装规格
10μl
级别
无动物源
浓度
≥95%(SDS-PAGE)
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
储存缓冲液
PBS, pH 7.2
生化机理
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. (Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells. (Microbial infection) Acts as a receptor for Adenovirus subgroup B2 and Ad3. (Microbial infection) Acts as a receptor for cultured Measles virus. (Microbial infection) Acts as a receptor for Herpesvirus 6/HHV-6. (Microbial infection) May act as a receptor for pathogenic bacteria Neisseria and Streptococcus pyogenes.
免疫原
Recombinant protein corresponding to Human CD46
宿主种属
小鼠(Mouse)
种属反应性
人(Human)
特异性
Human CD46
阳性对照
WB: HeLa, K562, A431, A549 and MCF-7 whole cell lysates Flow Cytometry: HeLa cells IF/ICC: HeLa cells
SDS-PAGE
150.0 KDa
偶联
Unconjugated
亚型
Mouse IgG1
克隆类型
单克隆抗体
轻链亚型
kappa
纯化方法
Protein A purified
克隆号
AB03/5B11
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical 10μl; ≥95%

Research chemical 10μl; ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl; ≥95%.

item number:Ab210969-10μl
Product model:10μl
level: 10μl; ≥95%
Lead Time:30days
sold 236 Items
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10μl

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