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Product details

名称

Recombinant CD41a Antibody (AF647)

分子类型

抗体

别名

血小板膜糖蛋白Ⅱb（CD41）单克隆抗体 | Anti-CD41a抗体 | CD41a抗体 | CD41a单抗

英文别名

货号

Ab213116-25T

包装规格

25T

级别

已验证

浓度

5 μL/test

储存温度

2-8°C储存,避光,禁止冷冻

运输条件

冰袋运输

稳定性与储存

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

储存缓冲液

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

防腐剂

0.05% Proclin300

生化机理

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed:9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity).

免疫原

Purified platelet membrane glycoproteins

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human CD41a

阳性对照

Flow Cytometry: Human peripheral blood platelets

偶联

AF647

亚型

Mouse IgG1

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

P50A23

Excitation(nm)

Red Laser(633nm)

Emission(nm)

668nm

Ex/Em(nm)

Ex:650nm;Em:668nm

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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