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Product details

名称

Recombinant CD45RO Antibody (FITC)

分子类型

抗体

别名

CD45RO单克隆抗体 | Anti-CD45RO抗体 | CD45RO抗体 | CD45RO鼠单抗

英文别名

B220 | CD45 antigen | CD45R | CD45RO | EC 3.1.3.48 | L-CA | LY5 | protein tyrosine phosphatase, receptor type, C | receptor-type tyrosine-protein phosphatase C | T200 glycoprotein | T200 leukocyte common antigen | T200receptor type, c polypeptide | B220 a

货号

Ab213949-100T

包装规格

100T

级别

已验证

浓度

5 μL/test

储存温度

2-8°C储存,避光,禁止冷冻

运输条件

冰袋运输

稳定性与储存

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

储存缓冲液

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

防腐剂

0.05% Proclin300

生化机理

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).(Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.

免疫原

IL-2 dependent T cell line, CA1

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human CD45RO

阳性对照

Flow Cytometry: Human peripheral blood lymphocytes.

偶联

FITC

亚型

Mouse IgG2a

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein G purified

克隆号

P08F59

Excitation(nm)

Blue Laser(488nm)

Emission(nm)

517nm

Ex/Em(nm)

Ex:498nm;Em:517nm

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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