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Product details

名称

Recombinant CD14 Antibody

分子类型

抗体

别名

英文别名

货号

Ab219610-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融.

储存缓冲液

PBS, pH 6.0

生化机理

Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.

免疫原

Human CD14 protein

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human CD14

阳性对照

Flow Cytometry: Human peripheral blood monocytes

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG2a

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

P25A37

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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