Recombinant TCR γ/δ Antibody

抗体

γδT细胞受体 | TCR γ/δ抗体 | TCR gamma/delata抗体 | TCR gamma+TCR delta抗体

CD_antigen=CD3d antibody | CD3D antibody | CD3G antibody | T cell antigen receptor delta polypeptide antibody | T cell antigen receptor gamma polypeptide antibody | T cell rearranging gene gamma antibody | T cell receptor delta antibody | T cell receptor

Ab219619-10μg

10μg

无动物源

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

PBS, pH 8.0

TCR gamma/delta (T-cell receptor gamma/delta) are specialized T-cells in the immune system. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory auto-destructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). However, a small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

C57BL/6J intraepithelial lymphocytes

亚美尼亚仓鼠(Armenian hamster)

小鼠(Mouse)

Mouse TCR γ/δ

Flow Cytometry: C57BL/6 mouse lymph node cells

150 kDa

Unconjugated

Armenian Hamster IgG

重组抗体

kappa

Protein A purified

P36A16

Whole IgG