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名称

Recombinant CD15/SSEA-1 Antibody

分子类型

抗体

别名

阶段特异性胚胎抗原-1 | CD15抗体 | FUT4抗体 | Anti-CD15/SSEA-1抗体 | 小鼠抗人CD15抗体

英文别名

货号

Ab219623-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

储存缓冲液

PBS, pH 6.0

生化机理

Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis (By similarity). In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.

免疫原

WERI-RB-1 retinoblastoma cell line

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human CD15

阳性对照

Flow Cytometry: THP-1 cells

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

P52C45

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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