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Product details

名称

Recombinant CD14 Antibody (AF750)

分子类型

抗体

别名

英文别名

货号

Ab223475-10T

包装规格

10T

级别

已验证

浓度

5 μL/test

储存温度

2-8°C储存,避光,禁止冷冻

运输条件

冰袋运输

稳定性与储存

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

储存缓冲液

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

防腐剂

0.05% Proclin300

生化机理

Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.

免疫原

Human Thymocytes followed by peripheral blood mononuclear cells.

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human CD14

阳性对照

Flow Cytometry: Human peripheral blood monocytes

偶联

AF750

亚型

Mouse IgG2a

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

P02C06

Excitation(nm)

Red Laser(633nm)

Emission(nm)

776nm

Ex/Em(nm)

Ex:752nm;Em:776nm

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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After Sales Services

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Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！