- exposure pathway： 眼部插入后全身吸收极少。当外用凝胶应用于与酒渣鼻相关的面部红斑成人患者时，血浆最大浓度(Cmax)和浓度-时间曲线下面积(AUC)分别为46 ± 62 pg/mL和417 ± 264 pg.hr/mL。这些数值在治疗第15天达到。
- Toxicity summary： 溴莫尼定是一种α肾上腺素能受体激动剂（主要是α-2型）。它在给药后两小时达到眼压降低的峰值。在动物和人体中的荧光光度研究表明，溴莫尼定具有双重作用机制，通过减少房水产生和增加葡萄膜巩膜外流。外用凝胶通过直接血管收缩减少红斑。
- Toxicity Data： LD50: 50 mg/kg (口服，小鼠) LD50: 100 mg/kg (口服，大鼠)
- Symptoms and Signs： 口服LD<sub>50</sub>在小鼠中为50 mg/kg，在大鼠中为100 mg/kg。
- Hazard categories and classifications： 急性毒性 3级 (100%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- Effects During Pregnancy and Lactation： 截至修订日期，未找到相关已发表信息。
Warm reminder：
Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！
Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.
Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！
Research chemical >98. 0%; HPLC
Research chemical >98. 0%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: >98. 0%; HPLC.
