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Product introduction
一种合成的非甾体雌激素,用于治疗更年期和绝经期疾病。它以前也曾用作动物的生长促进剂。根据致癌物年度报告第四版(NTP 85-002,1985),二乙烯基雌酚已被列为已知致癌物。
Chinese name
己烯雌酚, 雌激素受体-α的激动剂
English name
4-[4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
Chinese alias
-
English alias
DES | 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | Diethylstilbesterol | Makarol | Stilbofolin | 4,4'-(Hex-3-ene-3,4-diyl)diphenol | Climaterine | Distilbene | Oestromensyl | (E)-4,4'-(hex-3-ene-3,4-diyl)diphenol | neo-Oestranol 1 | New-Estranol 1 |
CAS number
56-53-1
molecular formula
C18H20O2
molecular weight
268.3
Exact mass
-
PSA
40.5
Logp
5.1
Safety
  • Toxicity summary: 雌激素扩散到其靶细胞并与蛋白质受体雌激素受体相互作用。靶细胞包括女性生殖道、乳腺、下丘脑和垂体。雌激素与其受体结合的效果导致下游增加性激素结合球蛋白(SHBG)、甲状腺结合球蛋白(TBG)和其他血清蛋白的肝脏合成,并抑制来自垂体前叶的促卵泡激素(FSH)。雌激素与孕激素的组合抑制下丘脑-垂体系统,减少促性腺激素释放激素(GnRH)的分泌。
  • Symptoms and Signs: 过量症状包括恶心和呕吐,女性可能出现撤退性出血。
  • Carcinogen Classification: 1,对人类有致癌性。(L135)
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Research chemical CAS 56-53-1 HPLC; ≥99%; 100mg

Research chemical CAS 56-53-1 HPLC; ≥99%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: HPLC; ≥99%; 100mg.

item number:B20591-100mg
Product model:100mg
level: HPLC; ≥99%; 100mg
Lead Time:30days
sold 418 Items
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