- Hazard summary： 从大气湿度中吸收水分时形成水合物；作为食品调味剂使用时安全；[JECFA] 皮肤和强眼刺激物；[Alfa Aesar MSDS] 参见硫胺素。
- exposure pathway： 口服；肠外（静脉、肌肉）。主要从十二指肠通过主动和被动过程吸收
- Toxicity summary： 据推测，硫胺素对内皮细胞的作用机制与通过重定向糖酵解通量减少细胞内蛋白质糖基化有关。硫胺素主要是维生素的运输形式，而活性形式是磷酸化硫胺素衍生物。目前已知的五种天然硫胺素磷酸衍生物为：硫胺素单磷酸(ThMP)、硫胺素二磷酸(ThDP)，有时也称为硫胺素焦磷酸(TPP)、硫胺素三磷酸(ThTP)，以及最近发现的腺苷硫胺素三磷酸(AThTP)和腺苷硫胺素二磷酸。每种衍生物都有独特的功能，但大多数都作为辅酶参与反应。
- Regulatory information： 新西兰EPA化学品清单状态：盐酸硫胺素：非危险
- Toxicity Data： LD50: 8224毫克/公斤(口服，小鼠)(A308) LD50: 3710毫克/公斤(口服，大鼠)(A308)
- Health Effects： 目前没有报告显示通过摄入食物和补充剂过量摄入硫胺素会产生不良影响。[维基百科]
- Other safety information： 化学品评估：评估-不太可能需要进一步监管以管理环境风险的化学品
- Hazard categories and classifications： 眼睛刺激物 2 (33.2%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2016.02.015
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Research chemical CAS 67-03-8 HPLC; ≥99%; 20mg
Research chemical CAS 67-03-8 HPLC; ≥99%; 20mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: HPLC; ≥99%; 20mg.
