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Product introduction

Larotaxel (XRP9881) 是一种紫杉烷类似物，具有抗紫杉烷抗性乳腺癌的临床前活性。Larotaxel (XRP9881) 通过促进微管蛋白装配和稳定微管发挥其细胞毒性作用，并最终通过细胞凋亡导致细胞死亡。Larotaxel (XRP9881) 具有穿越血脑屏障的能力，对 P-糖蛋白 1 的亲和力比 Docetaxel 低得多。 Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel.

Specs ⸢ View details ⸥

Chinese name

Larotaxel, 微管蛋白稳定剂

English name

Larotaxel

Chinese alias

拉罗他赛

English alias

[(1S,2S,3R,4S,7R,9S,11R,13R,16S)-4,13-diacetyloxy-1-hydroxy-16-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-15,18,18-trimethyl-12-oxo-6-oxapentacyclo[12.3.1.03,11.04,7.09,11]octadec-14-en-2-yl] benzoate | XRP 9881 | L

CAS number

156294-36-9

molecular formula

C45H53NO14

molecular weight

831.9 g/mol

Exact mass

≥98%

PSA

210.000 Å²

Logp

2.7

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Larotaxel HPLC≥98% 5mg

Name: Larotaxel HPLC≥98% 5mg
Brand: 源叶
SKU: B21907-5mg

Yuanye Larotaxel HPLC≥98% 5mg, CAS 156294-36-9, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：B21907-5mg

Product model：5mg

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Lead Time：30days

sold 349 Items

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Larotaxel HPLC≥98% 5mg

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