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Product introduction

产品说明 Bryostatin 1 是一种天然的大环内酯类化合物，从苔藓虫 Bugula neritina 中分离出来，也是一种有效的中枢神经系统 (CNS) 渗透性的 PKC 调节剂。Bryostatin 1 以 Ki 值为 8.07 nM 和 0.45 nM 分别结合到分离的 Munc13-1 的 C1 域和全长的 Munc13-1 蛋白。Bryostatin 1 具有抗癌，抗炎，神经保护，抗 HIV-1 感染的特性。 Product Explanation Bryostatin 1 is a natural macrolide compound isolated from Bugula neritina, a moss worm, and an effective PKC regulator of central nervous system (CNS) permeability. Bryostatin 1 binds to the C1 domain of isolated Munc13-1 and the full-length Munc13-1 protein with Ki values of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has characteristics of anti-cancer, anti-inflammatory, neuroprotective, and anti HIV-1 infection.

Specs ⸢ View details ⸥

Chinese name

Bryostatin 1,蛋白激酶C激活剂

English name

Bryostatin 1

Chinese alias

苔藓抑素1

English alias

NSC-339555 | Bryostatin 1, >=99%, solid | BRN 4349157 | Bryostatin-1 | Q27095907 | (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-o

CAS number

83314-01-6

molecular formula

C47H68O17

molecular weight

905.03 g/mol

Exact mass

≥98%

PSA

240.000 Å²

Logp

4.000

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