Share to

Overview

Specs

Technical Documents

Articles

reviews

Consult

returns

Product introduction

AG-490 (Tyrphostin AG 490)是EGFR抑制剂，IC50为100nM，比对ErbB2的抑制性高135倍，对Lck，Lyn，Btk，Syk和Src无活性。Tyrphostin AG has been used to block IL-6 cytokine signaling to study its effects on glial cell reactivity. AG 490 has also been used as a JAK2 inhibitor in human umbilical vein endothelial cells AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR with IC50 of 0.1 μM, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src. Tyrphostin AG has been used to block IL-6 cytokine signaling to study its effects on glial cell reactivity. AG 490 has also been used as a JAK2 inhibitor in human umbilical vein endothelial cells

Specs ⸢ View details ⸥

Chinese name

酪氨酸激酶抑制剂AG 490, 表皮生长因子受体抑制剂

English name

AG-490 (Tyrphostin B42)

Chinese alias

酪氨酸激酶抑制剂AG 490

English alias

BS-15205 | C72336 | EX-A118 | NCGC00016014-03 | SR-01000076153-3 | (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide | IDI1_033866 | SMP2_000154 | Diflunisalum [INN-Latin] | s1143 | HMS1361F18 | BMK1-D1 | NCGC00016014-07 | SR-01000076153 | EU-010

CAS number

133550-30-8

molecular formula

C17H14N2O3

molecular weight

294.3 g/mol

Exact mass

PSA

93.400 Å²

Logp

2.4

Technical Documents

「No technical documents」

「No upstream and downstream information yet」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！

Research chemical CAS 133550-30-8 HPLC ≥98% 10mg

Name: Research chemical CAS 133550-30-8 HPLC ≥98% 10mg
Brand: 上海源叶
SKU: B27879-10mg

Research chemical CAS 133550-30-8 HPLC ≥98% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：B27879-10mg

Product model：10mg

level： HPLC ≥98% 10mg

Lead Time：30days

sold 26 Items

Ask Solution engineer

Qty

Research chemical CAS 133550-30-8 HPLC ≥98% 10mg

Recommended for you