Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

BIO 1211,α4β1（VLA-4）抑制剂, 整合素 α4β1 抑制剂

英文别名

AKOS024457866 | SCHEMBL1223367 | BDBM50074661 | MS-31193 | Q27075284 | (S)-1-{(S)-2-[3-Carboxy-2-((1S,5S)-4-methyl-2-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetylamino}-pentanoylamino)-propionylamino]-3-methyl-butyryl}-pyrrolidine-2-carboxylic acid | L-PROLINE,

货号

B288747-100mg

包装规格

100mg

级别

Moligand™

浓度

≥98%

产品介绍

BIO-1211 是高度选择性的、具有口服活性的 α4β1 (VLA-4) 抑制剂，其对 α4β1 和 α4β7 的 IC50 值分别为 4 nM 和 2 μM。

生化机理

选择性，高亲和力α4β1（极晚期抗原4； VLA-4）抑制剂；对活化形式的α4β1（KD = 70 pM; IC50 =0.004μM）的选择性显示200倍的选择性。对其他一系列整联蛋白具有选择性（对于α1β1，α5β1和α6β1，IC50>100μM）。

作用类型

抑制剂

作用机制

整合素 α4β1 抑制剂

序列

MPUPA-LDVP

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！