弹力蛋白A

B329642-1mg

1mg

≥95%

链霉菌产生的抗生素弹力蛋白A已显示出对寄生虫曲霉产生的黄曲霉毒素具有很强的抑制活性。对黄曲霉毒素产生的这种抑制作用没有强烈的生长抑制作用，从而对产生黄曲霉毒素的真菌没有影响。在经弹力蛋白A处理的寄生曲霉中观察到核糖体蛋白丰度降低。实验表明，弹性蛋白A显着降低了| A中编码黄曲霉毒素调节基因和生物合成酶（omtA，ver-1和pksA）的基因的表达。 Blasticidin A, an antibiotic produced by Streptomyces, has been shown to have strong inhibitory activity toward aflatoxin production by|Aspergillus parasiticus|. This inhibition of aflatoxin production does not have a strong growth suppressing impact toward the aflatoxin-producing fungi. There was a decrease in abundance of ribosomal protein observed in Blasticidin A treated A. parasitici. Experiments indicate that Blasticidin A significantly reduced the expression of genes encoding aflatoxin regulatory gene and biosynthetic enzymes (omtA, ver-1, and pksA) in|A. parasiticus.