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Product introduction
贝胆碱是2-甲基胆碱的碳酸酸酯。一种缓慢水解的毒蕈碱受体激动剂,无烟碱效应,以其氯化物盐形式使用,用于增加平滑肌张力,如腹部手术后胃肠道治疗、胃食管反流病治疗,以及作为非阻塞性尿潴留治疗中导尿的替代方案。它具有毒蕈碱受体激动剂的作用。它是一种氨基甲酸酯和季铵离子。
Chinese name
bethanechol, M 1 受体激动剂
English name
2-carbamoyloxypropyl(trimethyl)azanium
Chinese alias
-
English alias
AB00053794_16 | BDBM39342 | SPBio_002993 | KBio3_001402 | NCGC00015245-07 | AB00053794-14 | BETHANECHOL [WHO-DD] | NCGC00015245-04 | NCGC00015245-06 | Spectrum4_000255 | AKOS025310166 | DivK1c_000179 | SCHEMBL37096 | 2-((Aminocarbonyl)oxy)-N,N,N-trimethyl
CAS number
674-38-4
molecular formula
C7H17N2O2+
molecular weight
161.22
Exact mass
-
PSA
52.3
Logp
0.000
Safety
  • Treatment: 硫酸阿托品是特异性解毒剂。成人推荐剂量为0.6毫克。可根据临床反应每两小时重复给药。12岁以下婴儿和儿童的推荐剂量为0.01毫克/千克(单次最大剂量为0.4毫克),根据需要每两小时重复给药,直至获得预期效果或阿托品的不良反应阻止进一步使用。除紧急情况可静脉给药外,皮下注射是首选给药方式。(L1712)
  • exposure pathway: 口服
  • Harmful effect: 神经节阻滞剂,如美加明和六甲双铵,可降低血压。与神经节阻滞剂合用贝胆碱需谨慎,因为可能导致低血压。乙酰胆碱酯酶抑制剂如多奈哌齐和利斯的明可能增加其他胆碱能激动剂如贝胆碱的不良反应。
  • Toxicity summary: 贝胆碱直接刺激副交感神经系统中的胆碱能受体,同时较小程度地刺激神经节。其主要作用是毒蕈碱样作用,对烟碱受体影响很小,对心血管系统的影响可忽略不计。
  • Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到关于哺乳期妇女的相关已发表信息。在动物实验中,胆碱能药物会增加催产素的释放,并对血清催乳素水平产生不同影响。对于已建立哺乳期的母亲,其催乳素水平可能不会影响其母乳喂养能力。
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bethanechol, M 1 receptoragonist; M 2 receptoragonist; M 3 receptoragonist; M 4 receptoragonist; M 5 receptoragonist 5mg

bethanechol, M 1 receptoragonist; M 2 receptoragonist; M 3 receptoragonist; M 4 receptoragonist; M 5 receptoragonist 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg.

item number:B608029-5mg
Product model:5mg
level: 5mg
Lead Time:30days
sold 825 Items
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Specifications:

5mg

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