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Product introduction

BMS-820132 是一种部分葡萄糖激酶 (glucokinase) 激活剂，AC50 为 29 nM。BMS-820132 可降低正常大鼠葡萄糖耐量试验 (OGTT) 模型中的葡萄糖水平，但不会降低 Zucker 糖尿病肥胖 (ZDF) 大鼠的葡萄糖水平。BMS-820132 具有继发于强效 GK 激活的药理学毒性。 BMS-820132 is an partial glucokinase (GK) activator with a AC50 of 29 nM. BMS-820132 decreases the glucose levels in glucose tolerance test (OGTT) model in normal rats, but not Zucker diabetic fatty (ZDF) rats. BMS-820132 exhibits pharmacological toxicity secondary to strong GK activation

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Chinese name

BMS-820132, 葡萄糖激酶激活剂

English name

BMS-820132

Chinese alias

BMS820132;compound 31

English alias

BMS820132;compound 31

CAS number

1001419-18-6

molecular formula

C26H33N6O7P

molecular weight

572.55 g/mol

Exact mass

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