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名称

BVDV-IN-1

英文名称

BVDV-IN-1

货号

B646716-5mg

包装规格

5mg

浓度

≥98%

储存温度

避光,-80℃储存

运输条件

超低温冰袋运输

产品介绍

BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV) , with an EC 50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC). In Vitro BVDV-IN-1 (compound 1.9) binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp). BVDV-IN-1 inhibits the replication of TSC-resistant BVDV variants in vitro. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

生化机理

BVDV-IN-1 是一种牛病毒性腹泻病毒（BVDV）非核苷抑制剂（NNI），EC 50 为 1.8 μM。BVDV-IN-1 可直接与 BVDV RdRp 的疏水口袋结合。BVDV-IN-1 对 NNI 硫代氨基甲酸乙酯耐药的 BVDV 具有抗病毒活性。

CAS号

345651-04-9

分子式

C20H22N4O

分子量

334.41 g/mol

Smiles

OCCN1CCN(C2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)CC1

溶解性

DMSO : 250 mg/mL (747.59 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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