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Product details

名称

BRM/BRG1 ATP Inhibitor-1

分子类型

小分子

别名

BRM/BRG1 ATP 抑制剂-1

英文名称

BRM/BRG1 ATP Inhibitor-1

货号

B647365-5mg

包装规格

5mg

级别

Moligand™

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

BRM/BRG1 ATP Inhibitor-1 是变构双 Brahma 同源物 (BRM)/SWI/SNF 相关的基质相关肌动蛋白依赖性调节剂，染色质亚家族 A 成员 2 和 BRG1/SMARCA4 ATP 酶活性抑制剂，IC50值低于 0.005 μM。 BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50s

CAS号

2270879-17-7

分子式

C11H9F3N4O2S

分子量

318.27 g/mol

PubChem编号

137701967

Isomeric SMILES

C1=C(C(=CN=C1F)CO)NC(=O)NC2=CC(=NS2)C(F)F

IIUPAC Name

1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)pyridin-4-yl]urea

INCHI

1S/C11H9F3N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)

InChi Key

CKYCAIAVJIFWPE-UHFFFAOYSA-N

Smiles

C1=C(C(=CN=C1F)CO)NC(=O)NC2=CC(=NS2)C(F)F

PubChem CID

137701967

溶解性

DMSO : 250 mg/mL (785.50 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

318.04 Da

单同位素质量Monoisotopic Mass

318.04 Da

拓扑极表面积Topological Polar Surface Area

115.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

366

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

1.6

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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