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Product introduction

Bruceantinol, a quassinoid isolated from Brucea javanica , inhibits pepper mottle virus in pepper Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability ( IC 50 =2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1 , PTTG1, survivin and c-Myc . Form:Solid IC50& Target:IC 50 : 2.4 pM (STAT3 DNA-binding ability)

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Chinese name

Bruceantinol

English name

Bruceantinol

Chinese alias

布鲁氏菌醇

English alias

DTXSID70415102 | CHEBI:3189 | Q27105980 | AKOS040760307 | BRUCEANTINOL | E88745 | HY-N8146 | C08750 | MS-30670 | methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-3-[(E)-4-acetyloxy-3,4-dimethylpent-2-enoyl]oxy-10,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-

CAS number

53729-52-5

molecular formula

C30H38O13

molecular weight

606.6 g/mol

Exact mass

≥98%

PSA

192.000 Å²

Logp

0.8

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