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Product introduction
BTK inhibitor 10 is a potent and orally active Bruton kinase (BTK) inhibitor, extracted from patent WO2018145525, example 33. BTK inhibitor 10 has a potential for rheumatoid arthritis treatment In Vivo BTK inhibitor 10 (oral gavage; 30 mg/kg; 21 days; once daily) has a significant improvement in arthritis symptoms in CIA mice. The damage of each of the 4 paws in mice is divided into 0-4 to calculate the total score of the limbs. After 21 days’ oral treatment, BTK030 reduces the arthritic score to 3.62 while the control group shows a value of 8.33 . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: DBA/1J mice injected with collagen as a CIA model Dosage: 30 mg/kg Administration: oral gavage; 21 days; once daily Result: Decreased arthritis scores significantly when it compares to control group. Form:Solid IC50& Target:IC50: Bruton kinase (BTK)
Chinese name
BTK inhibitor 10
English name
BTK inhibitor 10
Chinese alias
BTK抑制剂10
English alias
-
CAS number
2241732-30-7
molecular formula
C25H23N5O3
molecular weight
441.48 g/mol
Exact mass
≥99%
PSA
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BTK inhibitor 10 5mg

BTK inhibitor 10 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥99%.

item number:B651233-5mg
Product model:5mg
level: 5mg; ≥99%
Lead Time:30days
sold 646 Items
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5mg

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