Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

BAN ORL 24

英文名称

BAN ORL 24

货号

B654527-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

避光,充氩,-80℃储存

运输条件

超低温冰袋运输

产品介绍

BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with K I value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic In Vitro BAN ORL 24 has antagonist for NOR and MOR (opioid receptor subtype) with IC 50 values of 50 μM and 0.224 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo BAN ORL 24 (10 mg/kg; i.v.) attenuates the duration of BPRIM97 thermal antinociception. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57BL/6 miceDosage: 10 mg/kg Administration: 10 mg/kg; i.v. Result: Caused inhibition of BPRIM97-induced antinociception at 90-min postinjection. Did not attenuate BPR1M97-induced antinociception in the tail-clip test after 30 min. IC50& Target:Ki: 0.24 nM (NOP in CHO cell),IC50: 50 μM (NOR),0.224 μM (MOR)

生化机理

BAN ORL 24 是一种痛觉素/孤儿素 FQ（N/OFQ）肽受体（NOP）拮抗剂。BAN ORL 24 对痛觉素（NOP）受体具有拮抗作用，在 CHO 细胞中的 K I 值为 0.24 nM。BAN ORL 24 可用于癌症和镇痛研究。

CAS号

1401463-54-4(DMSO)

分子式

C27H35N3O2.2HCl

分子量

506.51 g/mol

Smiles

C1CC(N(C1)CC2=CC=CC=C2)C(=O)NCCCN3CCC4(CC3)C5=CC=CC=C5CO4.Cl.Cl

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！