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Product details

名称

BRCA1-IN-2

英文名称

BRCA1-IN-2

货号

B654592-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC 50 of 0.31 μM and a K d of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT) 2 /protein interactions IC50& Target:IC50: 0.31 μM (BRCA1), Kd: 0.3 μM (BRCA1)

生化机理

BRCA1-IN-2（化合物 15）是一种细胞渗透性蛋白-蛋白相互作用（PPI）抑制剂，其 IC 50 为 0.31 μM，K d 为 0.3 μM，通过破坏 BRCA1 (BRCT) 2 与蛋白的相互作用而显示出抗肿瘤活性。

CAS号

1622262-55-8(DMSO)

分子式

C26H33N4O7P

分子量

544.54 g/mol

Smiles

C1=CC=C(C=C1)CCCCNC(=O)CNC(=O)C(COP(=O)(O)O)NC(=O)CCC2=CNC3=CC=CC=C32

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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