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Product details

名称

BIIL-260 hydrochloride

别名

BIIL-260盐酸盐

英文名称

BIIL-260 hydrochloride

货号

B654923-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB 4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB 4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB 4 receptor on isolated human neutrophil cell membranes with K i values of 1.7 nM In Vitro BIIL-260 hydrochloride potently inhibits LTB 4 -induced intracellular Ca 2+ release in human neutrophils with IC 50 value of 0.82 nM MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:Ki: 1.7 nM (LTB 4 receptor)

生化机理

盐酸 BIIL-260 是一种强效长效口服活性白三烯 B（4）受体 LTB 4 拮抗剂，具有抗炎活性。BIIL-260 盐酸盐能以可饱和、可逆和竞争性的方式与 LTB 4 受体相互作用，具有抗炎活性。

CAS号

192581-24-1(DMSO)

分子式

C30H31ClN2O3

分子量

503.03 g/mol

Smiles

CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCC3=CC=CC(=C3)COC4=CC=C(C=C4)C(=N)N.Cl

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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