Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

BPR1M97

英文名称

BPR1M97

货号

B655796-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with K i values of 1.8 and 4.2 nM, respectively. BPR1M97 shows high potency and blood-brain barrier penetration, and produces potent antinociceptive effects In Vivo BPR1M97 (1.8 mg/kg; s.c.; once) demonstrates antinociception in a murine model of cancer pain . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male wild-type C57BL/6 mice (25-30 g) Dosage: 1.8 mg/kg Administration: Subcutaneous injection (s.c.); once Result: Demonstrated antinociception in a murine model of cancer pain. IC50& Target:Ki: 1.8 nM (MOP), 4.2 nM (NOP)

生化机理

BPR1M97 是一种双效μ阿片受体（MOP）和神经肽-orphanin FQ 肽（NOP）受体激动剂，其 K i 值分别为 1.8 和 4.2 nM。BPR1M97 具有很高的药效和血脑屏障穿透性，可产生强效的抗镇痛作用。

CAS号

2059904-66-2(DMSO)

分子式

C18H18Cl2N2O

分子量

349.25 g/mol

Smiles

O=C(NCC1N(C)CCC2=C1C=CC=C2)C3=CC=C(Cl)C(Cl)=C3

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！