Bortezomib-d8

硼替佐米-d8

Bortezomib-d8

B659013-1mg

1mg

≥98%

-20°C储存,充氩

超低温冰袋运输

Bortezomib-d 8 is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor , and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apo Appearance:Solid In Vitro:Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the phar Biological Activity:Bortezomib-d 8 is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor , and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apo

C19H17D8BN4O4

392.29 g/mol

OB([C@H](CC(C)C)NC(C(NC(C1=NC=CN=C1)=O)([2H])C([2H])([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)O