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Product details

名称

BIO5192 hydrate

别名

BIO5192 水合物

英文名称

BIO5192 hydrate

货号

B659154-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存,干燥

运输条件

超低温冰袋运输

产品介绍

BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d Appearance:Solid IC50& Target:α4β1 1.8 nM (IC 50 ) α9β1 138 nM (IC 50 ) α2β1 1053 nM (IC 50 ) α4β7 >500 nM (IC 50 ) In Vivo:The combination of BIO5192 hydrate (1mg/kg; i.v.) and Plerixafor (5mg/kg; s.c.) exert an additive effect on progenitor mobilization. BIO5192 hydrate (30mg/kg; s.c; bid; during days 5 through 14) delays paralysis associated with EAE (experimental a Biological Activity:BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d

分子式

C38H46Cl2N6O8S.1/2H2O

分子量

826.79 g/mol

Smiles

O=[S](N(CCC1)[C@@H]1C(N[C@H](C(O)=O)CCNC([C@H](CC(C)C)N(C)C(CC(C=C2)=CC=C2NC(NC(C=CC=C3)=C3C)=O)=O)=O)=O)(C4=CC(Cl)=CC(Cl)=C4)=O.O.[1/2]

溶解性

DMSO : ≥ 100 mg/mL (120.95 mM)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！