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名称

BMSpep-57 hydrochloride

别名

BMSpep-57 盐酸盐

英文名称

BMSpep-57 hydrochloride

货号

B659281-1mg

包装规格

1mg

浓度

≥99%

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hy Appearance:Solid IC50& Target:IC50: 7.68 nM (PD-1/PD-L1 interaction) In Vitro:In a ELISA competition assay, BMSpep-57 inhibits PD-1/PD-L1 binding up to 98.1% 300 nM. And it shows a concentration dependent inhibition of PD-1/PD-L1 binding with an IC 50 of 7.68 nM. BMSpep-57 induced high levels of IL-2 at 1 µM and 500 nM concent Biological Activity:BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68u2009nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-5

分子式

C89H127ClN24O19S

分子量

1904.63 g/mol

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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