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Product introduction
Valproic acid-d6 是 Valproic acid 的氘代物。Valproic acid (VPA; 2-Propylpentanoic Acid) 是一种 HDAC 抑制剂,IC50 值为 0.5-2 mM,抑制 HDAC1 的活性,(IC50,400 μM),同时可诱导 HDAC2 的降解。Valproic acid 激活 Notch1 信号并抑制小细胞肺癌 (SCLC) 细胞的增殖。Valproic acid 可用于癫痫、双相情感障碍和偏头痛等的研究。 Valproic acid-d6 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches .
Chinese name
丙戊酸-d6
English name
Valproic acid-d6
Chinese alias
丙戊酸-D6 | 2-(丙基-3,3,3-d3)戊酰基-5,5-5-d3酸
English alias
VPA-d6 | 2-Propylpentanoic Acid-d6 | 2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid | Pentanoic-5,5,5-d3 acid, 2-(propyl-3,3,3-d3)- (9CI) | 5,5,5,5',5',5'-Hexadeuterovalproic acid | Valproic-5,5,5,5',5',5'-D6 acid
CAS number
87745-18-4
molecular formula
C8H10D6O2
molecular weight
150.25 g/mol
Exact mass
≥98 atom% D,≥98%(CP)
PSA
37.300 Ų
Logp
2.8
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Research chemical CAS 87745-18-4 98%; 1mg

Research chemical CAS 87745-18-4 98%; 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 98%; 1mg.

item number:B71884-1mg
Product model:1mg
level: 98%; 1mg
Lead Time:30days
sold 106 Items
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