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Product introduction
Pimozide 是 dopamine receptor 的拮抗剂,对 dopamine D2,D3 和 D1 受体的 Ki 值分别为 1.4 nM,2.5 nM 和 588 nM,同时对 α1-adrenoceptor 也有较高亲和性,Ki 值为 39 nM;Pimozide 也是 STAT3 和 STAT5 的抑制剂。 产品应用: Pimozide (Orap, R6238) 是一种 Dopamine Receptors 的拮抗剂,对dopamine D3,D2和D1受体的Ki值分别为0.83 nM,3.0 nM和6600 nM。Pimozide 在5-HT1A和α1-adrenoceptor 处也表现出结合亲和力,对应的Ki值分别为310 nM、39 nM。Pimozide 是一种具有抗肿瘤活性的抗精神病药物,可抑制 STAT3 和 STAT5 活性。
Chinese name
Pimozide, 多巴胺受体拮抗剂
English name
Pimozide
Chinese alias
3-[1-[4,4-双(4-氟苯基)丁基]哌啶-4-基]-1H-苯并咪唑-2-酮 | 匹莫齐特
English alias
MLS000028410 | Pimozidum | PIMOZIDE [USP MONOGRAPH] | Prestwick0_000308 | HMS501D08 | Opiran | BSPBio_001439 | GTPL90 | KBio2_006061 | Pimozide (USAN:USP:INN:BAN:JAN) | Prestwick2_000308 | 5-24-02-00367 (Beilstein Handbook Reference) | Lopac0_000946 | NSC
CAS number
2062-78-4
molecular formula
C28H29F2N3O
molecular weight
461.55 g/mol
Exact mass
-
PSA
35.600 Ų
Logp
6.3
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Research chemical CAS 2062-78-4 HPLC ≥95% 25mg

Yuanye Research chemical CAS 2062-78-4 HPLC ≥95% 25mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:B73363-25mg
Product model:25mg
level: HPLC ≥95% 25mg
Lead Time:30days
sold 248 Items
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