
- exposure pathway: 摄入
- Toxicity summary: 槟榔碱是槟榔中负责中枢神经系统作用的主要活性成分。槟榔碱已被与尼古丁比较;然而,尼古丁主要作用于烟碱型乙酰胆碱受体。槟榔碱已知是毒蕈碱乙酰胆碱M1、M2、M3受体和M4的部分激动剂,这被认为是其副交感作用(如瞳孔收缩、支气管收缩等)的主要原因。(维基百科)槟榔碱在浓度高于50 μg/ml时对人牙龈成纤维细胞具有细胞毒性,通过消耗细胞内硫醇和抑制线粒体活性(P<0.05)。此外,细胞以剂量依赖性方式在G2/M期明显停滞。(A15351)
- Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
- Toxicity Data: LD50:100 mg/kg,在小鼠中皮下给药(维基百科)
- Health Effects: 瞳孔收缩,支气管收缩。
- Hazard categories and classifications: 致癌性2(50%)
- Carcinogen Classification: IARC未列出。
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Research chemical CAS 63-75-2 HPLC ≥98% 100mg
Yuanye Research chemical CAS 63-75-2 HPLC ≥98% 100mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.




