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Product introduction
槟榔碱是一种四氢吡啶,是在1-位具有甲基、3-位具有甲氧羰基的1,2,5,6-四氢吡啶。一种在槟榔中发现的生物碱,它作为毒蕈碱乙酰胆碱的激动剂。它具有代谢物和毒蕈碱激动剂的作用。它是一种甲酯、吡啶生物碱、四氢吡啶和烯酸酯。
Chinese name
槟榔碱, M 1 受体激动剂
English name
methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
Chinese alias
-
English alias
Lopac0_000049 | Methyl N-methyltetrahydronicotinate | Q423515 | Spectrum_000055 | BSPBio_000324 | L000795 | 63-75-2 (free) | Arecholine | DTXCID502617 | KBioSS_000435 | Methyl 1,2,5, 6-tetrahydro-1-methylnicotinate | Arecaidine methyl ester | Prestwick1_0
CAS number
63-75-2
molecular formula
C8H13NO2
molecular weight
155.19
Exact mass
-
PSA
29.5
Logp
0.3
Safety
  • exposure pathway: 摄入
  • Toxicity summary: 槟榔碱是槟榔中负责中枢神经系统作用的主要活性成分。槟榔碱已被与尼古丁比较;然而,尼古丁主要作用于烟碱型乙酰胆碱受体。槟榔碱已知是毒蕈碱乙酰胆碱M1、M2、M3受体和M4的部分激动剂,这被认为是其副交感作用(如瞳孔收缩、支气管收缩等)的主要原因。(维基百科)槟榔碱在浓度高于50 μg/ml时对人牙龈成纤维细胞具有细胞毒性,通过消耗细胞内硫醇和抑制线粒体活性(P<0.05)。此外,细胞以剂量依赖性方式在G2/M期明显停滞。(A15351)
  • Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
  • Toxicity Data: LD50:100 mg/kg,在小鼠中皮下给药(维基百科)
  • Health Effects: 瞳孔收缩,支气管收缩。
  • Hazard categories and classifications: 致癌性2(50%)
  • Carcinogen Classification: IARC未列出。
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Research chemical CAS 63-75-2 HPLC ≥98% 100mg

Yuanye Research chemical CAS 63-75-2 HPLC ≥98% 100mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:B74705-100mg
Product model:100mg
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Lead Time:30days
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