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Product introduction

（±）18-HETE是花生四烯酸的细胞色素P450（CYP450）代谢产物的外消旋形式。当由CYP2E1同工型形成时，18-HETE占（R）异构体的100％。它以剂量依赖性方式刺激兔肾的血管舒张，其中18（S）-HETE不影响灌注压力。18-HETE对ATPase活性的影响可忽略不计。在1 µM（±）处，18-HETE已显示出完全阻断20-HETE诱导的肾小动脉血管收缩的作用。 (±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. It stimulates vasodilation of the rabbit kidney, in a dose dependent manner, where 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. At 1 μM (±)18-HETE has shown to completely blocks 20-HETE-induced vasoconstriction of renal arterioles.

Specs ⸢ View details ⸥

Chinese name

(±)18-HETE

English name

(±)18-HETE

Chinese alias

English alias

CAS number

133268-58-3

molecular formula

C20H32O3

molecular weight

320.5 g/mol

Exact mass

PSA

57.500 Å²

Logp

4.800

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18-hydroxy-5(Z), 8(Z), 11(Z), 14(Z)-ETA >97% 50ug

Name: 18-hydroxy-5(Z), 8(Z), 11(Z), 14(Z)-ETA >97% 50ug
Brand: 源叶
SKU: B76050-50ug

Yuanye 18-hydroxy-5(Z), 8(Z), 11(Z), 14(Z)-ETA >97% 50ug, CAS 133268-58-3, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

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18-hydroxy-5(Z), 8(Z), 11(Z), 14(Z)-ETA >97% 50ug

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