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Product introduction
现有证据表明,5-溴-5-硝基-1,3-二氧杂环己烷作为化妆品成分在浓度高达0.1%的情况下是安全的,除非其与胺或酰胺反应可能形成亚硝胺或亚硝酰胺的情况除外。
Chinese name
5-溴代-5-硝基-1,3-二氧杂环己烷
English name
5-bromo-5-nitro-1,3-dioxane
Chinese alias
-
English alias
1,3-Dioxane, 5-bromo-5-nitro- | 5-BROMO-5-NITRO-1,3-DIOXANE [INCI] | FT-0620143 | Bronidox L | EN300-7381687 | DTXCID9024560 | XVBRCOKDZVQYAY-UHFFFAOYSA-N | 5-Brom-5-nitro-1,3-dioxan [German] | 5-Bromo-5-nitro-m-dioxane | Bronidox | U184I9QBNM | 5-Bromo-5
CAS number
30007-47-7
molecular formula
C4H6BrNO4
molecular weight
212.00
Exact mass
≥98%
PSA
64.3
Logp
0.3
Safety
  • Treatment: EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
  • exposure pathway: 口服(L626);吸入(L626);皮肤(L626)
  • Toxicity summary: 溴硝丙二醇可能作为氧化剂,导致必需酶中游离巯基的氧化。最可能的蛋白质靶标之一是在眼睛、鼻子、嘴巴和肺的感觉神经(三叉神经)中表达的TRPA1离子通道。这会影响它们的活性,并可能导致细胞损伤、细胞死亡和/或细胞凋亡。它还可能与胺和酰胺反应形成亚硝胺或亚硝酰胺。亚硝胺可能致癌。
  • Regulatory information: 新西兰EPA化学品清单状态:5-溴-5-硝基-1,3-二氧杂环己烷:没有单独批准,但可在适当的团体标准下使用
  • Toxicity Data: LD50:590 mg/kg(小鼠,口服);LD50:455 mg/kg(大鼠,口服);LD50:31 mg/kg(大鼠,腹腔注射);LD50:2500 µg(小鼠,皮肤);LD50:2500 µg(大鼠,皮肤)
  • Health Effects: 在浓度>0.1%时可引起明显的皮肤和眼睛刺激。作为甲醛释放剂,溴硝二氧杂环己烷可能引起理发师和处理含溴硝二氧杂环己烷清洁剂的工人的过敏性接触性皮炎。它既不是诱变性的,也不是致畸性的。
  • Symptoms and Signs: 急性剂量可引起皮肤和眼睛刺激。如果吸入,可能引起呼吸道和粘膜刺激。如果摄入,有害。可能影响行为/中枢神经系统(震颤、惊厥、兴奋)。
  • Other safety information: 化学品评估:评估-溴硝醇和溴硝丙二醇
  • Hazard categories and classifications: 皮肤腐蚀-1C类
  • Carcinogen Classification: 无致癌性迹象(未被IARC列出)。(L135)
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Research chemical CAS 30007-47-7 10% 1L

Research chemical CAS 30007-47-7 10% 1L, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

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