BIBB是合成酰胺、大环酰胺、烯酮和炔酮的重要试剂。 应用： α-溴异丁酰溴已用于： 1.作为原子转移自由基聚合（ATRP）引发剂，用于氧化石墨烯表面上羟基的官能化； 2.形成一个 N保护的卤代二烯酰胺，在铜（I）和叔胺存在下提供四元和五元内酰胺； 3.通过与低聚己内酯二醇反应制备聚己内酯大分子引发剂[4] 通过与固定在外表面的ATRP引发剂反应制备介孔二氧化硅纳米粒子。 BIBB is an important reagent in the synthesis of amides, macrocyclic amides, ketenes, and alkynic ketones. Application： α-Bromoisobutyryl bromide has been used: as atom transfer radical polymerization (ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide. to form an N-protected halodienamide which provided four- and five-membered lactams in the presence of copper (I) and a tertiary amine. in preparation of polycaprolactone macroinitiator via reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.