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Product introduction

红霉素B（12-脱氧红霉素A）是通过发酵红霉素放线菌（Saccharopolyspora erythreae）产生的红霉素次要共代谢物。尽管红霉素B比红霉素A效力低，但它具有广谱的抗生素活性。红霉素B在半合成红霉素的结构活性关系研究中起着不可或缺的作用，但没有到临床阶段。 Erythromycin B (12-deoxyerythromycin A) is a minor co-metabolite of erythromycin produced by fermentation of Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity,albeit less potent than erythromycin A. Erythromycin B played an integral part of the structure activityrelationship studies of semi-synthetic erythromycins, however none reached clinical development.

Specs ⸢ View details ⸥

Chinese name

红霉素B

English name

Erythromycin B

Chinese alias

English alias

AN686JJ1YI | Abbot 24091 | (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetra

CAS number

527-75-3

molecular formula

C37H67NO12

molecular weight

717.93 g/mol

Exact mass

PSA

174.000 Å²

Logp

3.900

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