- Hazard summary： 在致死剂量喂养研究中导致大鼠嗜睡；在高剂量吸入研究中导致流泪、嗜睡和肾脏损伤；[RTECS] 刺激物和催泪剂；吸入高度毒性；针对血液、肾脏和中枢神经系统；[Aldrich MSDS]
- reactive group： 卤代有机化合物
- First aid measures： 5. 转移到医疗机构。(EPA, 1998)
- Harmful effect： 催泪剂 - 一种刺激眼睛并诱导流泪的物质。
- Fire potential： 自熄性
- Toxicity Data： LC50 (小鼠) = 200 mg/m3/2h
- Cleanup Methods： 生产3,3-双(氯甲基)氧杂环丁烷的污水生物澄清。
- reactivity profile： 3,3-双(氯甲基)氧杂环丁烷是一种氯代醚。
- Air and water reaction： 与空气无快速反应。与水无快速反应。
- Hazard categories and classifications： 急性毒性 4 (97.5%)
- Non-human toxic extract： 合成了一系列含有碘甲基、烷氧基甲基和烷基氨基甲基的氧杂环丁烷。测定了这些化合物在小鼠和猫中的毒性和支气管扩张活性。含碘和烷氧基的氧杂环丁烷毒性较低，含氮的氧杂环丁烷比合成的初始产物3,3-双(氯甲基)氧杂环丁烷毒性更高。所有含氧杂环丁烷环的化合物都表现出明显的支气管扩张作用。3-(氯甲基)-3-(丁氧基甲基)氧杂环丁烷、3,3-二(丙氧基甲基)氧杂环丁烷和3-(氯甲基)-3-(碘甲基)氧杂环丁烷与氨茶碱具有相同的支气管扩张作用。
- Personal protective equipment (PPE)： 紧急情况下，佩戴正压、需求式、全面罩自给式呼吸器(SCBA)或需求式供气呼吸器，并配备逃生SCBA和全包覆式耐化学腐蚀服。(EPA, 1998)
- Protective Action Standards (PAC)： PAC-3: 7.0 [mg/m3]
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3, 3-(chloromethyl)oxacyclobutane 98% 5g
3, 3-(chloromethyl)oxacyclobutane 98% 5g Macklin 78-71-7, available in complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials
