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Product introduction
小檗碱是一种小檗碱生物碱、有机杂五环化合物、生物碱抗生素和植物抗真菌剂。它具有抗衰老、抗氧化、代谢物、降糖剂、EC 3.1.3.48(蛋白酪氨酸磷酸酶)抑制剂、抗肿瘤药物、抗脂质药物、EC 3.1.1.8(胆碱酯酶)抑制剂、EC 3.1.1.7(乙酰胆碱酯酶)抑制剂、EC 1.1.1.21(醛还原酶)抑制剂、EC 3.1.1.4(磷脂酶A2)抑制剂、钾通道阻滞剂、EC 3.4.14.5(二肽基肽酶IV)抑制剂、EC 1.13.11.52(吲哚胺2,3-双加氧酶)抑制剂、EC 3.4.21.26(脯氨酰寡肽酶)抑制剂、EC 1.1.1.141[15-羟基前列腺素脱氢酶(NAD(+))]抑...
Chinese name
小檗碱, CYP2D6 抑制剂
English name
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene
Chinese alias
-
English alias
AKOS002141363 | BERBERINE [VANDF] | CCG-35898 | KBio2_006726 | GNF-PF-4545 | 9,10-DIMETHOXY-5,6-DIHYDRO(1,3)DIOXOLO(4,5-G)ISOQUINO(3,2-A)ISOQUINOLIN-7-IUM | CHEBI:16118 | BSPBio_002156 | cid_12456 | SBI-0051613.P002 | NSC646666 | CAS-633-65-8 | ACon1_0019
CAS number
2086-83-1
molecular formula
C20H18NO4+
molecular weight
336.4
Exact mass
-
PSA
40.8
Logp
3.6
Safety
  • Hazard summary: 胎儿体重降低(归因于母体体重的变化),但在小鼠和大鼠中未观察到致畸性;[生殖毒理学]
  • Toxicity summary: 血根碱[13甲基(1,3)苯并二氧杂环戊烯(5,6-c)-1,3-二氧杂环戊烯(4,5)菲啶鎓]通过作用于Na+-K+-ATPase跨膜蛋白杀死动物细胞。另一方面,据报道小檗碱会导致细胞毒性并不利影响DNA的合成。研究报告了这些生物碱的各种药理特性,例如,它们具有抗菌、抗哮喘、抗癌、抗炎和抗糖尿病活性。
  • Hepatotoxicity: 药物类别:草药和膳食补充剂
  • Effects During Pregnancy and Lactation: 尚未在人类中进行研究,以确定小檗碱是否会影响男性生育能力或增加出生缺陷的几率超过背景风险。通常,父亲或精子捐献者的暴露不太可能增加妊娠风险。有关更多信息,请参阅MotherToBaby事实表父系暴露,网址为https://mothertobaby.org/fact-sheets/paternal-exposures-pregnancy/。
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chemical ≥99%(HPLC) 20mg

chemical ≥99%(HPLC) 20mg CAS 2086-83-1, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:B875003-20mg
Product model:20mg
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Lead Time:30days
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