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Product introduction

Information BAY 2402234 BAY 2402234 is a novel and selective dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 1.2 nM. Targets DHODH (Cell-free assay) 1.2 nM In vitro BAY 2402234 induces differentiation and inhibits proliferation in AML cell lines across multiple AML subtypes. In vivo BAY 2402234 shows strong monotherapy efficacy and induces differentiation in AML xenograft models in vivo. Cell Research(from reference) Cell lines：MOLM-13, HEL, MV4-11, SKM-1 and THP-1 cell lines Concentrations：0.1nM to 1μM Incubation Time：96 h

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Chinese name

BAY 2402234, 二氢烟酸脱氢酶（醌）抑制剂

English name

BAY 2402234

Chinese alias

English alias

AKOS040741291 | s8847 | N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide | Orludodstat | N-(2-Chloro-6-fluorophenyl)-4-(4-ethyl-4,5-dihydro-3-(hydr

CAS number

2225819-06-5

molecular formula

C21H18ClF5N4O4

molecular weight

520.84 g/mol

Exact mass

PSA

94.500 Å²

Logp

4.103

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BAY-2402234 ≥98% 5mg

Name: BAY-2402234 ≥98% 5mg
Brand: 麦克林
SKU: B880283-5mg

BAY-2402234 ≥98% 5mg CAS 2225819-06-5, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：B880283-5mg

Product model：5mg

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Lead Time：30days

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BAY-2402234 ≥98% 5mg

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