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Product introduction
HG-7-85-01 是一种Bcr-Abl,PDGFRα,Kit和Src激酶的野生型和看门突变形式的 II 型 ATP 竞争性抑制剂。HG-7-85-01 抑制 T315I 突变型Bcr-Abl(T315I mutantBcr-Abl) 激酶,KDR和RET,IC50为 3 nM,20 nM 和 30 nM,对其他激酶的抑制作用很小或没有抑制作用 (IC50>2 μM)。HG-7-85-01 通过诱导细胞凋亡 (apoptosis) 和抑制细胞周期进程来抑制细胞增殖。
Chinese name
3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
English name
3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
Chinese alias
-
English alias
-
CAS number
1258391-13-7
molecular formula
C31H31F3N6O2S
molecular weight
608.7 g/mol
Exact mass
≥99%
PSA
119.000 Ų
Logp
5.000
Technical Documents
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3-{2-[(cyclopropylcarbonyl)amino][1, 3]thiazolo[5, 4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide 5mg

3-{2-[(cyclopropylcarbonyl)amino][1, 3]thiazolo[5, 4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥99%.

item number:C1275678-5mg
Product model:5mg
level: 5mg; ≥99%
Lead Time:30days
sold 578 Items
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Specifications:

5mg

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