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Product introduction

CB-839 (Telaglenastat) 是一种有效的，选择性的 glutaminase 抑制剂，对重组人GAC的 IC50 为 24 nM。CB-839(Telaglenastat)可诱导自噬并具有抗肿瘤活性。 Biochemical mechanism: Cell permeable: yes Primary Target GLS1 Reversible: yes Target IC50: 23 nM & 28 nM, respectively, using murine kidney and brain homogenates

Specs ⸢ View details ⸥

Chinese name

CB-839, 谷氨酰胺酶肾脏同工酶，线粒体抑制剂

English name

CB-839

Chinese alias

English alias

A14396 | U6CL98GLP4 | A857288 | EX-A1310 | MFCD28167826 | AS-75090 | HMS3873G13 | NCGC00356145-11 | WHO 10815 | CB839; CB 839 pound>>Telaglenastat,

CAS number

1439399-58-2

molecular formula

C26H24F3N7O3S

molecular weight

571.57 g/mol

Exact mass

PSA

160.000 Å²

Logp

3.6

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